TNFRSF8 (Human) Recombinant Protein
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Specification
Product Description
Human TNFRSF8 partial recombinant protein with His tag in C-terminus expressed in Baculovirus cells.
Sequence
ADPFPQDRPFEDTCHGNPSHYYDKAVRRCCYRCPMGLFPTQQCPQRPTDCRKQCEPDYYLDEADRCTACVTCSRDDLVEKTPCAWNSSRVCECRPGMFCSTSAVNSCARCFFHSVCPAGMIVKFPGTAQKNTVCEPASPGVSPACASPENCKEPSSGTIPQAKPTPVSPATSSASTMPVRGGTRLAQEAASKLTRAPDSPSSVGRPSSDPGLSPTQPCPEGSGDCRKQCEPDYYLDEAGRCTACVSCSRDDLVEKTPCAWNSSRTCECRPGMICATSATNSCARCVPYPICAAETVTKPQDMAEKDTTFEAPPLGTQPDCNPTPENGEAPASTSPTQSLLVDSQASKTLPIPTSAPVALSSTGKHHHHHH
Host
Viruses
Theoretical MW (kDa)
39.5
Form
Liquid
Preparation Method
Baculovirus expression system
Purification
chromatographic
Purity
> 95% as determined by SDS-PAGE.
Storage Buffer
Solution (1 mg/mL) containing 1X PBS, pH 7.4, 10% glycerol.
Storage Instruction
Store at 4°C for one weeks and should be stored at -20°C to -80°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid repeated freeze/thaw cycles. -
Applications
SDS-PAGE
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Gene Info — TNFRSF8
Entrez GeneID
943Protein Accession#
P28908Gene Name
TNFRSF8
Gene Alias
CD30, D1S166E, KI-1
Gene Description
tumor necrosis factor receptor superfamily, member 8
Omim ID
153243Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
CD30 antigen|CD30L receptor|Ki-1 antigen|OTTHUMP00000001783|cytokine receptor CD30|lymphocyte activation antigen CD30
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Interactome
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