IL18BP (Human) Recombinant protein
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Specification
Product Description
Human IL18BP (O95998, 31 a.a. - 194 a.a) partial recombinant protein with hIgG-His tag at C-terminal expressed in Sf9 cells.
Sequence
ADPTPVSQTT TAATASVRST KDPCPSQPPV FPAAKQCPAL EVTWPEVEVP LNGTLSLSCV ACSRFPNFSI LYWLGNGSFI EHLPGRLWEG STSRERGSTG TQLCKALVLE QLTPALHSTN FSCVLVDPEQ VVQRHVVLAQ LWAGLRATLP PTQEALPSSH SSPQQQGLEP KSCDKTHTCP PCPAPELLGG PSVFLFPPKP KDTLMISRTP EVTCVVVDVS HEDPEVKFNW YVDGVEVHNA KTKPREEQYN STYRVVSVLT VLHQDWLNGK EYKCKVSNKA LPAPIEKTIS KAKGQPREPQ VYTLPPSRDE LTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV LDSDGSFFLY SKLTVDKSRW QQGNVFSCSV MHEALHNHYT QKSLSLSPGK HHHHHH.
Host
insect
Theoretical MW (kDa)
44.9
Form
Liquid
Preparation Method
Insect cell (Sf9) expression system
Purity
> 90% by SDS-PAGE.
Storage Buffer
In PBS, pH 7.4 and 10% glycerol
Storage Instruction
Store at 4°C for 2~4 week. For long term storage store at -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — IL18BP
Entrez GeneID
10068Protein Accession#
O95998Gene Name
IL18BP
Gene Alias
IL18BPa
Gene Description
interleukin 18 binding protein
Omim ID
604113Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is an inhibitor of the proinflammatory cytokine IL18. This protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. This protein is constitutively expressed and secreted in mononuclear cells. The expression of this protein can be enhanced by IFN-gamma. An elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
MC51L-53L-54L homolog gene product|OTTHUMP00000179141|OTTHUMP00000179143
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Disease
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