BMP4 (Human) Recombinant Protein
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Specification
Product Description
Human BMP4 (P12644) recombinant protein expressed in Escherichia coli.
Sequence
SPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR.
Host
Escherichia coli
Theoretical MW (kDa)
13
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 95% by HPLC and SDS PAGE
Storage Buffer
BMP-4 was lyophilized from a 0.2um filtered concentrated (1mg/mL) solution in 20mM Na2CO3 buffer, pH 9.0.
Storage Instruction
Store at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles.
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Applications
SDS-PAGE
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Gene Info — BMP4
Entrez GeneID
652Protein Accession#
P12644Gene Name
BMP4
Gene Alias
BMP2B, BMP2B1, MCOPS6, ZYME
Gene Description
bone morphogenetic protein 4
Omim ID
112262Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein. [provided by RefSeq
Other Designations
bone morphogenetic protein 2B
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Interactome
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Pathway
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Disease
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