BDNF (Human) Recombinant Protein
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Specification
Product Description
Human BDNF (P23560, 129 a.a. - 247 a.a) partial-length recombinant protein with His-tag at N-terminal expressed in Escherichia coli.
Sequence
MGSSHHHHHHSSGLVPRGSHMHSDPARRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTLTIKRGR.
Host
Escherichia coli
Theoretical MW (kDa)
15.8
Form
Liquid
Preparation Method
Escherichia coli expression system
Purity
> 85% by SDS-PAGE
Storage Buffer
20mM Tris-HCl buffer (pH 8.0) and 10% glycerol.
Storage Instruction
Store, frozen at -20°C for longer periods of time.
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Applications
SDS-PAGE
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Gene Info — BDNF
Entrez GeneID
627Protein Accession#
P23560Gene Name
BDNF
Gene Alias
MGC34632
Gene Description
brain-derived neurotrophic factor
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq
Other Designations
neurotrophin
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Interactome
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Pathway
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Disease
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