CCL7 (Human) Recombinant Protein
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Specification
Product Description
Human CCL7 (Q7Z7Q8, 34 a.a. - 109 a.a.) partial recombinant protein expressed in CHO cells.
Sequence
QPVGINTSTTCCYRFINKKIPKQRLESYRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL
Host
Mammals
Theoretical MW (kDa)
10 ~ 18
Form
Lyophilized
Preparation Method
_x005F_x000D__x000D_ Mammalian cell (CHO) expression system_x005F_x000D__x000D_
Purity
> 98% as analyzed by SDS-PAGE.
Endotoxin Level
< 0.2 EU/ ug of protein (gel clotting method)
Activity
Human CCL7 EC50 < 1.5 ug/mL, measured on Ca2+ mobilization assay in CHO-K1/ Galpha15/hCCR1 cells (human Galpha15 and human CCR1 stably expressed in CHO-K1 cells).
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS. Reconstitute the lyophilized powder in ddH2O up to 100 ug/mL.
Storage Instruction
Store at 4°C for 1 week. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — CCL7
Entrez GeneID
6354Protein Accession#
Q7Z7Q8Gene Name
CCL7
Gene Alias
FIC, MARC, MCP-3, MCP3, MGC138463, MGC138465, NC28, SCYA6, SCYA7
Gene Description
chemokine (C-C motif) ligand 7
Omim ID
158106Gene Ontology
HyperlinkGene Summary
This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq
Other Designations
monocyte chemoattractant protein 3|monocyte chemotactic protein 3|small inducible cytokine A7 (monocyte chemotactic protein 3)
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