IL20 (Human) Recombinant Protein
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Specification
Product Description
Human IL20 (Q9NYY1, 25 a.a. - 176 a.a.) partial recombinant protein expressed in Escherichia coli.
Sequence
LKTLNLGSCVIATNLQEIRNGFSEIRGSVQAKDGNIDIRILRRTESLQDTKPANRCCLLRHLLRLYLDRVFKNYQTPDHYTLRKISSLANSFLTIKKDLRLCHAHMTCHCGEEAMKKYSQILSHFEKLEPQAAVVKALGELDILLQWMEETE
Host
Escherichia coli
Theoretical MW (kDa)
17.6
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 95% by SDS-PAGE
Endotoxin Level
< 1 EU per 1 ug of protein (determined by LAL method)
Activity
The ED50 was determined by the cell proliferation assay using human IL-20Ralpha and human IL-20beta co-transfected murine BaF3 pro-B cells is < 0.5 ng/ml, corresponding to a specific activity of > 2.0 x 106 IU/mg.
Storage Buffer
Lyophilized from sterile distilled Water up to 0.1 - 1.0 mg/ml
Storage Instruction
Store at 4°C to 8°C for 1 week. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — IL20
Entrez GeneID
50604Protein Accession#
Q9NYY1Gene Name
IL20
Gene Alias
IL-20, IL10D, MGC96907, ZCYTO10
Gene Description
interleukin 20
Omim ID
605619Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. [provided by RefSeq
Other Designations
OTTHUMP00000034617|OTTHUMP00000034618|four alpha helix cytokine
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