CLK1 (Human) Recombinant Protein
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Specification
Product Description
Human CLK1 (NM_004071.2, 1 a.a. - 484 a.a.) full-length recombinant protein with GST-His tag expressed in Sf9 cells.
Host
insect
Theoretical MW (kDa)
86.69499999999979
Form
Liquid
Preparation Method
Insect cell (Sf9) expression system
Purification
One-step affinity purification using GSH-agarose
Concentration
0.139 ug/uL
Activity
0.4 pmol/ug x min
Quality Control Testing
2 ug/lane SDS-PAGE Stained with Coomassie Blue
Storage Buffer
In 50 mM Tris-HCl, 100 mM NaCl, pH 8.0. (5 mM DTT, 4 mM reduced glutathione, 20% glycerol)
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawingNote
Result of activity analysis
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Applications
Functional Study
SDS-PAGE
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Gene Info — CLK1
Entrez GeneID
1195Protein Accession#
NM_004071.2Gene Name
CLK1
Gene Alias
CLK, CLK/STY, STY
Gene Description
CDC-like kinase 1
Omim ID
601951Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
CDC28/CDC2-like kinase|dual specificity protein kinase CLK1|protein tyrosine kinase STY
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