VTN monoclonal antibody, clone VN58-1
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Specification
Product Description
Mouse monoclonal antibody raised against VTN.
Immunogen
Human VTN.
Host
Mouse
Reactivity
Human
Specificity
This antibody specifically reacts with an epitope in the region of amino acids 1-130 of human vitronectin. It does not react with bovine vitronectin, and this antibody does not interfere with vitronectin-mediated adhesion.
Form
Lyophilized
Isotype
IgG1
Recommend Usage
ELISA (1:3000)
Western Blot (5-10 ug/mL)
Immunohistochemistry (Frozen sections) (5-10 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 10 mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
Storage Instruction
Store at 4°C on dry atmosphere, lyophilized antibodies are stable at least 2 year.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry (Frozen sections)
Enzyme-linked Immunoabsorbent Assay
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Gene Info — VTN
Entrez GeneID
7448Gene Name
VTN
Gene Alias
V75, VN, VNT
Gene Description
vitronectin
Omim ID
193190Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. [provided by RefSeq
Other Designations
complement S-protein|epibolin|serum spreading factor|somatomedin B|vitronectin (serum spreading factor, somatomedin B, complement S-protein)
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Interactome
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Pathway
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Disease
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