ITGA6 monoclonal antibody, clone MP 4F10
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to ITGA6 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]
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Specification
Product Description
Mouse monoclonal antibody raised against native ITGA6.
Immunogen
Native purified ITGA6 from SW1222 human colorectal cell line.
Host
Mouse
Reactivity
Human
Specificity
Reacts with alpha 6. MP 4F10 can be used in clinical studies for tumour grading - stains moderately and well-differentiated colorectal adenocarcinoma.
Form
Liquid
Isotype
IgG2b
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to ITGA6 on formalin-fixed paraffin-embedded human placenta. [antibody concentration 3 ug/ml]Immunoprecipitation
Flow Cytometry
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Gene Info — ITGA6
Entrez GeneID
3655Gene Name
ITGA6
Gene Alias
CD49f, DKFZp686J01244, FLJ18737, ITGA6B, VLA-6
Gene Description
integrin, alpha 6
Gene Ontology
HyperlinkGene Summary
The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
integrin alpha chain, alpha 6|integrin alpha6B
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Interactome
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Pathway
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Disease
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Publication Reference
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Expression of integrin subunits in the human infant breast correlates with morphogenesis and differentiation.
Anbazhagan R, Bartkova J, Stamp G, Pignatelli M, Gusterson B.
The Journal of Pathology 1995 Jul; 176(3):227.
Application：IHC-Fr, Human, Necropsy breast specimens.
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Expression of integrin subunits in the human infant breast correlates with morphogenesis and differentiation.
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