KRT19 monoclonal antibody, clone A53-B/A2 (Biotin)
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Specification
Product Description
Mouse monoclonal antibody raised against native KRT19.
Immunogen
Native purified KRT19 from human breast adenocarcinoma cell line (MCF-7).
Host
Mouse
Theoretical MW (kDa)
40
Reactivity
Human
Specificity
This antibody reacts with Rod domain of cytokeratin 19 (40 KDa) in human tissue. Cytokeratin 19 is not expressed in hepatocytes; it is often co-expressed with cytokeratin 7.
Form
Liquid
Conjugation
Biotin
Concentration
1 mg/mL
Isotype
IgG2a
Quality Control Testing
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide).
Storage Instruction
Store at 4°C. Do not freeze.
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Applications
Western Blot (Cell lysate)
Western Blotting analysis (reducing conditions) of whole cell lysate of MCF-7 (human breast adenocarcinoma cell line).
Lane 1, 2 : Immunostaining with KRT19 monoclonal antibody, clone BA-17 (Cat # MAB0861).
Lane 3, 4 : Immunostaining with KRT19 monoclonal antibody, clone A53-B/A2 (Cat # MAB0862).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunocytochemistry
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
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Gene Info — KRT19
Entrez GeneID
3880Gene Name
KRT19
Gene Alias
CK19, K19, K1CS, MGC15366
Gene Description
keratin 19
Omim ID
148020Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq
Other Designations
40-kDa keratin intermediate filament|cytokeratin 19|keratin, type I cytoskeletal 19|keratin, type I, 40-kd
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Interactome
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