NEFH monoclonal antibody, clone NAP4
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot of rat cortex lysate showing specific immunolableing of the ~ 200k NEFH protein.
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Specification
Product Description
Mouse monoclonal antibody raised against native NEFH.
Immunogen
Native purified bovine NEFH.
Host
Mouse
Theoretical MW (kDa)
200
Reactivity
Bovine
Form
Liquid
Isotype
IgG1
Recommend Usage
Western Blot (1:5000)
Immunofluorescence (1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Tissue lysate)
Western blot of rat cortex lysate showing specific immunolableing of the ~ 200k NEFH protein.Immunofluorescence
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Gene Info — NEFH
Entrez GeneID
4744Protein Accession#
P12036Gene Name
NEFH
Gene Alias
NFH
Gene Description
neurofilament, heavy polypeptide
Gene Ontology
HyperlinkGene Summary
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq
Other Designations
neurofilament triplet H protein|neurofilament, heavy polypeptide 200kDa
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Interactome
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Pathway
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Disease
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