CD36 monoclonal antibody, clone SMf
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Specification
Product Description
Mouse monoclonal antibody raised against native CD36.
Immunogen
Native purified from human tonsil cells and PBMC.
Host
Mouse
Reactivity
Human
Specificity
human CD36.
Form
Liquid
Isotype
IgM
Recommend Usage
Flow Cytometry (1 ug/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In 100 mM BBS, pH 8.2
Storage Instruction
Store at 4°C.
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Applications
Western Blot
Immunohistochemistry (Frozen sections)
Flow Cytometry
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Gene Info — CD36
Entrez GeneID
948Gene Name
CD36
Gene Alias
CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3
Gene Description
CD36 molecule (thrombospondin receptor)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
CD36 antigen|CD36 antigen (collagen type I receptor, thrombospondin receptor)|PAS-4 protein|cluster determinant 36|fatty acid translocase|glycoprotein IIIb|leukocyte differentiation antigen CD36|platelet glycoprotein IV|scavenger receptor class B, member
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Interactome
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Pathway
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Disease
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Publication Reference
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Changes of the major sperm maturation-associated epididymal protein HE5 (CD52) on human ejaculated spermatozoa during incubation.
Yeung CH, Perez-Sanchez F, Schroter S, Kirchhoff C, Cooper TG.
Molecular Human Reproduction 2001 Jul; 7(7):617.
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Membrane glycoprotein CD36: a review of its roles in adherence, signal transduction, and transfusion medicine.
Greenwalt DE, Lipsky RH, Ockenhouse CF, Ikeda H, Tandon NN, Jamieson GA.
Blood 1992 Sep; 80(5):1105.
Application:Flow Cyt, Func, Neutralization, Human, Mouse, CMK, HEL, M-07 cells, Monocytes, Platelets.
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Changes of the major sperm maturation-associated epididymal protein HE5 (CD52) on human ejaculated spermatozoa during incubation.
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