INS monoclonal antibody, clone 336F 20B11 AF2 BA4
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant INS.
Immunogen
Recombinant protein corresponding to human INS.
Host
Mouse
Reactivity
Human
Specificity
This antibody recognizes natural and recombinant human insulin.
Form
Liquid
Isotype
IgG1, kappa
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS
Storage Instruction
Store at 4°C.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — INS
Entrez GeneID
3630Gene Name
INS
Gene Alias
ILPR, IRDN
Gene Description
insulin
Gene Ontology
HyperlinkGene Summary
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq
Other Designations
OTTHUMP00000011161|OTTHUMP00000011162|OTTHUMP00000196038|proinsulin
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Interactome
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Pathway
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Disease
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