DES monoclonal antibody, clone D33
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Specification
Product Description
Mouse monoclonal antibody raised against DES.
Immunogen
Native purified human DES.
Host
Mouse
Reactivity
Human
Specificity
This antibody is highly reactive with desmin. On immunoblots, only the 52 KDa desmin band is stained. This antibody stains muscle cells in human tissues. No detectable reactivity with GFAP, keratin, vimentin or neurofilament.
Form
Liquid
Isotype
IgG1
Recommend Usage
Immunohistochemistry (1:100)
The optimal working dilution should be determined by the end user.Storage Buffer
In 150 mM PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Frozen sections)
Immunofluorescence
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Gene Info — DES
Entrez GeneID
1674Gene Name
DES
Gene Alias
CMD1I, CSM1, CSM2, FLJ12025, FLJ39719, FLJ41013, FLJ41793
Gene Description
desmin
Gene Ontology
HyperlinkGene Summary
This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq
Other Designations
OTTHUMP00000064865|intermediate filament protein
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Interactome
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Pathway
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Disease
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