HIST3H3 (phospho S10) monoclonal antibody, clone 4B6 (SureLight 488)
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human HIST3H3.
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding S10 of human HIST3H3.
Host
Rabbit
Reactivity
Human
Form
Liquid
Conjugation
SureLight 488
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (5 uL/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of HeLa cells with HIST3H3 (phospho S10) monoclonal antibody, clone 4B6 (SureLight 488) (Cat # MAB23429). Untreated and unstained as negative control (blue) or untreated (red) or treated with nocodazole (green). -
Gene Info — HIST3H3
Entrez GeneID
8290Gene Name
HIST3H3
Gene Alias
H3.4, H3/g, H3FT, H3t, MGC126886, MGC126888
Gene Description
histone cluster 3, H3
Omim ID
602820Gene Ontology
HyperlinkGene Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq
Other Designations
H3 histone family, member T|OTTHUMP00000037945|histone 3, H3
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