CXCR1 monoclonal antibody, clone 2B8A1
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human CXCR1.
Immunogen
Recombinant protein corresponding to human CXCR1.
Host
Mouse
Theoretical MW (kDa)
39.8
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CXCR1-hIgGFc transfected HEK293 cell lysates with CXCR1 monoclonal antibody, clone 2B8A1 (Cat # MAB21491).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CXCR1 monoclonal antibody, clone 2B8A1 (Cat # MAB21491). -
Gene Info — CXCR1
Entrez GeneID
3577Protein Accession#
P25024Gene Name
CXCR1
Gene Alias
C-C, C-C-CKR-1, CD128, CD181, CDw128a, CKR-1, CMKAR1, IL8R1, IL8RA, IL8RBA
Gene Description
chemokine (C-X-C motif) receptor 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq
Other Designations
receptor|alpha|interleukin-8 receptor type 1|interleukin-8 receptor type A
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Interactome
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Pathway
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Disease
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