CDC45L monoclonal antibody, clone AD-3

Catalog # MAB19489

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Size:100 uL
Price: USD $ 428.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

Western blot analysis of Jurkat cell lysate with CDC45L monoclonal antibody.

  • Specification

    Product Description

    Rabbit monoclonal antibody raised against synthetic peptide of human CDC45L.

    Immunogen

    A synthetic peptide corresponding to human CDC45L.

    Host

    Rabbit

    Reactivity

    Human, Mouse, Rat

    Form

    Liquid

    Purification

    Affinity purification

    Isotype

    IgG

    Recommend Usage

    Immunocytochemistry (1:50-1:200)
    Immunofluorescence (1:50-1:200)
    Immunohistochemistry (1:50-1:200)
    Flow Cytometry (1:50)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

    Storage Instruction

    Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot (Cell lysate)

    Western blot analysis of Jurkat cell lysate with CDC45L monoclonal antibody.

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Immunocytochemistry

    Immunofluorescence

    Flow Cytometry

  • Gene Info — CDC45L

    Entrez GeneID

    8318

    Protein Accession#

    O75419

    Gene Name

    CDC45L

    Gene Alias

    CDC45, CDC45L2, PORC-PI-1

    Gene Description

    CDC45 cell division cycle 45-like (S. cerevisiae)

    Omim ID

    603465

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenlyation sites of this gene are reported. [provided by RefSeq

    Other Designations

    CDC45 (cell division cycle 45, S.cerevisiae, homolog)-like|CDC45-like|CDC45-related protein|cell division cycle 45-like 2|human CDC45

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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