BAK1 monoclonal antibody, clone 2H9H7
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: BAK1-hIgGFc transfected HEK293 cell lysates with BAK1 monoclonal antibody, clone 2H9H7 (Cat # MAB17939).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with BAK1 monoclonal antibody, clone 2H9H7 (Cat # MAB17939).
Flow Cytometry
Flow cytometric analysis of HeLa cells with BAK1 monoclonal antibody, clone 2H9H7 (Cat # MAB17939) (Green). Red: Negative Control.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human BAK1.
Immunogen
Recombinant protein corresponding to amino acids 29-187 of human BAK1.
Host
Mouse
Theoretical MW (kDa)
23.4
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: BAK1-hIgGFc transfected HEK293 cell lysates with BAK1 monoclonal antibody, clone 2H9H7 (Cat # MAB17939).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with BAK1 monoclonal antibody, clone 2H9H7 (Cat # MAB17939).Flow Cytometry
Flow cytometric analysis of HeLa cells with BAK1 monoclonal antibody, clone 2H9H7 (Cat # MAB17939) (Green). Red: Negative Control. -
Gene Info — BAK1
Entrez GeneID
578Protein Accession#
Q16611Gene Name
BAK1
Gene Alias
BAK, BAK-LIKE, BCL2L7, CDN1, MGC117255, MGC3887
Gene Description
BCL2-antagonist/killer 1
Omim ID
600516Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq
Other Designations
BCL2-like 7 protein|Bcl-2 homologous antagonist/killer|OTTHUMP00000016211|OTTHUMP00000039620|apoptosis regulator BAK|pro-apoptotic protein BAK
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Interactome
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Disease
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