FMR1 monoclonal antibody, clone 1D10
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of HEK293T cells (Lane 1: transfected with pCMV6-ENTRY control and Lane 2: transfected with pCMV6-ENTRY FMR1 cDNA) with FMR1 monoclonal antibody, clone 1D10 (Cat # MAB16366).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung with FMR1 monoclonal antibody, clone 1D10 (Cat # MAB16366).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human FMR1.
Immunogen
Recombinant protein corresponding to amino acids 36-279 of human FMR1 from E. coli.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG2b
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.3 (50% glycerol, 1% BSA, 0.02% sodium azide).
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of HEK293T cells (Lane 1: transfected with pCMV6-ENTRY control and Lane 2: transfected with pCMV6-ENTRY FMR1 cDNA) with FMR1 monoclonal antibody, clone 1D10 (Cat # MAB16366).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human lung with FMR1 monoclonal antibody, clone 1D10 (Cat # MAB16366). -
Gene Info — FMR1
Entrez GeneID
2332Protein Accession#
Q06787Gene Name
FMR1
Gene Alias
FMRP, FRAXA, MGC87458, POF, POF1
Gene Description
fragile X mental retardation 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). [provided by RefSeq
Other Designations
OTTHUMP00000024197|premature ovarian failure 1
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Interactome
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Disease
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