PDCD1 monoclonal antibody, clone J116
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with PDCD1 monoclonal antibody, clone J116 (Cat # MAB16293).
Flow Cytometry
Flow cytometric analysis of human PD-1 transfected cells with PDCD1 monoclonal antibody, clone J116 (Cat # MAB16293).
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Specification
Product Description
Mouse monoclonal antibody raised against human PDCD1.
Immunogen
Human PDCD1.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (20 ug/mL)
Immunohistochemistry (Frozen sections)
Immunoprecipitation
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.09% sodium azide).
Storage Instruction
Store at 4°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil with PDCD1 monoclonal antibody, clone J116 (Cat # MAB16293).Immunohistochemistry (Frozen sections)
Immunoprecipitation
Flow Cytometry
Flow cytometric analysis of human PD-1 transfected cells with PDCD1 monoclonal antibody, clone J116 (Cat # MAB16293). -
Gene Info — PDCD1
Entrez GeneID
5133Protein Accession#
Q15116Gene Name
PDCD1
Gene Alias
CD279, PD1, SLEB2, hPD-1, hPD-l
Gene Description
programmed cell death 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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