PDCD1 recombinant monoclonal antibody, clone F1-2A8
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Specification
Product Description
Llama recombinant monoclonal antibody raised against synthetic peptide corresponding to amino acids 25 - 167 of human PD-1.
Antibody Species
Llama
Immunogen
Original antibody is raised against a synthetic peptide corresponding to amino acids 25 - 167 of human PD-1
Reactivity
Human
Form
Liquid
Conjugation
Unconjugated
Purification
affinity chromatography
Concentration
1 mg/mL
Isotype
sdAb
Recommend Usage
ELISA (10 μg/ml)
Flow cytometry (10 μg/ml)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS
Storage Instruction
Store in working aliquots at -20°C for 1 year.
Aliquot to avoid repeated freezing and thawing.Note
Optimal dilutions for each application to be determined by the researcher.
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Applications
Enzyme-linked Immunoabsorbent Assay
ELISA analysis of human PD-1 using anti-PD-1 recombinant monoclonal antibody, clone F1-2A8 (Cat # RAB03744).Flow Cytometry
Flow-cytometry analysis of PD-1 transfected 293 cells using human anti-PD-1 recombinant monoclonal antibody, clone F1-2A8 (Cat # RAB03744). -
Gene Info — PDCD1
Entrez GeneID
5133Protein Accession#
Q15116Gene Name
PDCD1
Gene Alias
CD279, PD1, SLEB2, hPD-1, hPD-l
Gene Description
programmed cell death 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq
Other Designations
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Interactome
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