CLTA/CLTB monoclonal antibody, clone CLC/1421
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with CLTA/CLTB monoclonal antibody, clone CLC/1421 (Cat # MAB14737).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human CLTA/CLTB.
Immunogen
Recombinant protein corresponding to N-terminus of human CLTA/CLTB.
Host
Mouse
Theoretical MW (kDa)
31-44
Reactivity
Human
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG2b, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
Western Blotting (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human pancreas with CLTA/CLTB monoclonal antibody, clone CLC/1421 (Cat # MAB14737).Immunofluorescence
Flow Cytometry
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Gene Info — CLTA
Entrez GeneID
1211Protein Accession#
P09496;P09497Gene Name
CLTA
Gene Alias
LCA
Gene Description
clathrin, light chain (Lca)
Omim ID
118960Gene Ontology
HyperlinkGene Summary
Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
OTTHUMP00000021365|OTTHUMP00000021366|clathrin, light polypeptide (Lca)|clathrin, light polypeptide A
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Gene Info — CLTB
Entrez GeneID
1212Protein Accession#
P09496;P09497Gene Name
CLTB
Gene Alias
LCB
Gene Description
clathrin, light chain (Lcb)
Omim ID
118970Gene Ontology
HyperlinkGene Summary
Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Other Designations
clathrin, light polypeptide|clathrin, light polypeptide (Lcb)
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Interactome
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Pathway
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Disease
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Publication Reference
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Structure of human clathrin light chains. Conservation of light chain polymorphism in three mammalian species.
Jackson AP, Parham P.
The Journal of Biological Chemistry 1988 Nov; 263(32):16688.
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Structure of human clathrin light chains. Conservation of light chain polymorphism in three mammalian species.
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