TAGLN monoclonal antibody, clone TAGLN/247
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human colon carcinoma with TAGLN monoclonal antibody, clone TAGLN/247 (Cat # MAB14444).
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human TAGLN.
Immunogen
Recombinant protein corresponding to full length human TAGLN.
Host
Mouse
Theoretical MW (kDa)
22
Reactivity
Human
Specificity
This antibody recognizes a 22kDa protein, identified as TAGLN, also designated SM22-alpha. It may cross-react with SM22-beta.
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/million cells in 0.1 mL)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS (0.05% BSA and 0.05% azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human colon carcinoma with TAGLN monoclonal antibody, clone TAGLN/247 (Cat # MAB14444).Immunofluorescence
Flow Cytometry
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Gene Info — TAGLN
Entrez GeneID
6876Protein Accession#
Q01995Gene Name
TAGLN
Gene Alias
DKFZp686P11128, SM22, SMCC, TAGLN1, WS3-10
Gene Description
transgelin
Omim ID
600818Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
SM22-alpha|transgelin variant 2
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Interactome
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Disease
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Publication Reference
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Purification and properties of transgelin: a transformation and shape change sensitive Actin-gelling protein.
Shapland C, Hsuan JJ, Totty NF, Lawson D.
The Journal of Cell Biology 1993 Jun; 121(5):1065.
Application：WB-Ti, Sheep, Aorta.
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Purification and properties of transgelin: a transformation and shape change sensitive Actin-gelling protein.
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