CTTN monoclonal antibody, clone 4C6
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis using CTTN monoclonal antibody, clone 4C6 (Cat # MAB10620) against HeLa (1) , A-431 (2) , MCF-7 (3) , SR-BR-3 (4) , HepG2 (5) and NIH/3T3 (6) cell lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues (upper) and tonsil tissues (bottom) using CTTN monoclonal antibody, clone 4C6 (Cat # MAB10620) with DAB staining.
Enzyme-linked Immunoabsorbent Assay
ELISA measurement of CTTN monoclonal antibody, clone 4C6 (Cat # MAB10620) .
-
Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant CTTN.
Immunogen
Recombinant protein corresponding to human CTTN.
Host
Mouse
Theoretical MW (kDa)
80
Reactivity
Human, Mouse
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunohistochemistry (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis using CTTN monoclonal antibody, clone 4C6 (Cat # MAB10620) against HeLa (1) , A-431 (2) , MCF-7 (3) , SR-BR-3 (4) , HepG2 (5) and NIH/3T3 (6) cell lysate.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues (upper) and tonsil tissues (bottom) using CTTN monoclonal antibody, clone 4C6 (Cat # MAB10620) with DAB staining.Enzyme-linked Immunoabsorbent Assay
ELISA measurement of CTTN monoclonal antibody, clone 4C6 (Cat # MAB10620) . -
Gene Info — CTTN
Entrez GeneID
2017Gene Name
CTTN
Gene Alias
EMS1, FLJ34459
Gene Description
cortactin
Omim ID
164765Gene Ontology
HyperlinkGene Summary
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Two splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq
Other Designations
1110020L01Rik|ems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate)|oncogene EMS1
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com