KRT7/KRT17 monoclonal antibody, clone C-46
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry staining of human pancreas (paraffin - embedded sections) with KRT7/KRT17 monoclonal antibody, clone C - 46 (Cat # MAB0859) .
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Specification
Product Description
Mouse monoclonal antibody raised against native KRT7/KRT17.
Immunogen
Native purified KRT7/KRT17 from cytoskeleton of human HeLa cell line.
Host
Mouse
Theoretical MW (kDa)
54, 46
Reactivity
Bovine, Human, Pig
Specificity
This antibody reacts with Cytokeratin peptides 7 and 17 (54 and 46 KDa).
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry staining of human pancreas (paraffin - embedded sections) with KRT7/KRT17 monoclonal antibody, clone C - 46 (Cat # MAB0859) .Immunocytochemistry
Immunoprecipitation
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Gene Info — KRT7
Entrez GeneID
3855Gene Name
KRT7
Gene Alias
CK7, K2C7, K7, MGC129731, MGC3625, SCL
Gene Description
keratin 7
Omim ID
148059Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq
Other Designations
cytokeratin 7|keratin, 55K type II cytoskeletal|keratin, simple epithelial type I, K7|keratin, type II cytoskeletal 7|sarcolectin|type II mesothelial keratin K7
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Gene Info — KRT17
Entrez GeneID
3872Gene Name
KRT17
Gene Alias
K17, PC, PC2, PCHC1
Gene Description
keratin 17
Gene Ontology
HyperlinkGene Summary
This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq
Other Designations
cytokeratin-17
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