CK2 Kinase (Human) Assay/Inhibitor Screening Assay Kit
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More Files
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Dose dependent curve of recombinant CK2 enzyme reaction.
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Specification
Product Description
CK2 Kinase (Human) Assay/Inhibitor Screening Assay Kit is a single-site, non-quantitative immunoassay for CK2 activity. Plates are pre-coated with a substrate corresponding to recombinant p53, which contains a serine residue that are phosphorylated by CK2 (Casein kinase II). The detector antibody specifically detects only the phosphorylated form of serine46 on p53.
Assay Type
Quantitative
Reactivity
Human
Regulation Status
For research use only (RUO)
Quality Control Testing
Dose dependent curve
Dose dependent curve of recombinant CK2 enzyme reaction.
Storage Instruction
Store the kit at 4°C.
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Applications
Functional Study
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Gene Info — CSNK2A1
Entrez GeneID
1457Gene Name
CSNK2A1
Gene Alias
CK2A1, CKII
Gene Description
casein kinase 2, alpha 1 polypeptide
Omim ID
115440Gene Ontology
HyperlinkGene Summary
Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene. [provided by RefSeq
Other Designations
CK2 catalytic subunit alpha|OTTHUMP00000029925|OTTHUMP00000029926|casein kinase II alpha 1 subunit|casein kinase II alpha subunit|protein kinase CK2
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Interactome
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Disease
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Publication Reference
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Protein kinase CK2 modulates apoptosis induced by resveratrol and epigallocatechin-3-gallate in prostate cancer cells.
Ahmad KA, Harris NH, Johnson AD, Lindvall HC, Wang G, Ahmed K.
Molecular Cancer Therapeutics 2007 Mar; 6(3):1006.
Application：Func, Human, ALVA-41 cells.
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Protein kinase CK2 modulates apoptosis induced by resveratrol and epigallocatechin-3-gallate in prostate cancer cells.
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