c-Src Kinase (Human) Assay/Inhibitor Screening Assay Kit

Catalog # KA0058

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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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Dose dependent curve of recombinant c-Src catalytic domain enzyme reaction.

  • Specification

    Product Description

    c-Src Kinase (Human) Assay/Inhibitor Screening Assay Kit is a single-site, non-quantitative immunoassay for kinase activity of recombinant catalytic domain of c-Src. Plates are pre-coated with a newly designed "Tyrosine kinase-binding module-1", which can easily bind recombinant catalytic domain of c-Src, subsequently activate c-Src kinase activity on a microtiter plate. The detector antibody is PY-39, an antibody that specifically detects the phosphotyrosine residue on recombinant catalytic domain of c-Src itself, which means that this kit measures the intensity of autophosphorylation of c-Src catalytic domain.

    Assay Type

    Quantitative

    Reactivity

    Human

    Regulation Status

    For research use only (RUO)

    Quality Control Testing

    Dose dependent curve

    Dose dependent curve of recombinant c-Src catalytic domain enzyme reaction.

    Storage Instruction

    Store the kit at 4°C.

    Note

    SRC (Human) Recombinant Protein (Cat# P6990) is a Src positive control designed to use for c-Src Kinase (Human) Assay/Inhibitor Screening Assay Kit (Cat# KA0058).

  • Applications

    Functional Study

  • Gene Info — SRC

    Entrez GeneID

    6714

    Gene Name

    SRC

    Gene Alias

    ASV, SRC1, c-SRC, p60-Src

    Gene Description

    v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)

    Omim ID

    190090

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq

    Other Designations

    OTTHUMP00000174476|OTTHUMP00000174477|proto-oncogene tyrosine-protein kinase SRC|protooncogene SRC, Rous sarcoma|tyrosine kinase pp60c-src|tyrosine-protein kinase SRC-1

  • Interactome
  • Pathway
  • Disease
  • Publication Reference
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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