PACRG 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PACRG full-length
Host
Human
Theoretical MW (kDa)
28.38
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PACRG antibody (H00135138-B01) by Western Blots.
SDS-PAGE Gel
PACRG transfected lysate.
Western Blot
Lane 1: PACRG transfected lysate ( 28.38 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PACRG
Entrez GeneID
135138GeneBank Accession#
BC044227.1Protein Accession#
NP_001073847.1Gene Name
PACRG
Gene Alias
FLJ32724, GLUP, HAK005771, PARK2CRG, RP3-495O10.2
Gene Description
PARK2 co-regulated
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000017729|OTTHUMP00000017730|molecular chaperone/chaperonin-binding protein|parkin co-regulated gene protein
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Interactome
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Disease
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