TRIM5 monoclonal antibody (M06), clone 2A6
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant TRIM5.
Immunogen
TRIM5 (NP_149023, 309 a.a. ~ 418 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SCAVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGKHYWEVDVSKKTAWILGVCAGFQPDAMCNIEKNENYQPKYGYWVIGLEEGVKCSAFQDSSF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (40); Rat (37)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — TRIM5
Entrez GeneID
85363GeneBank Accession#
NM_033034Protein Accession#
NP_149023Gene Name
TRIM5
Gene Alias
RNF88, TRIM5alpha
Gene Description
tripartite motif-containing 5
Omim ID
608487Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Five alternatively spliced transcript variants for this gene have been described. However, the full length nature of two of the variants has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000069811|OTTHUMP00000069812|tripartite motif protein TRIM|tripartite motif protein TRIM5|tripartite motif-containing protein 5 alpha
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Interactome
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Disease
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