PLA2G12B (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human PLA2G12B partial ORF ( NP_115951.2, 78 a.a. - 187 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
PGYKPQEPNGCGSYFLGLKVPESMDLGIPAMTKCCNQLDVCYDTCGANKYRCDAKFRWCLHSICSDLKRSLGFVSKVEAACDSLVDTVFNTVWTLGCRPFMNSQRAACIC
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Interspecies Antigen Sequence
Mouse (95); Rat (96)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PLA2G12B
Entrez GeneID
84647GeneBank Accession#
NM_032562Protein Accession#
NP_115951.2Gene Name
PLA2G12B
Gene Alias
FKSG71, GXIIB, GXIIIsPLA2, MGC138151, PLA2G13
Gene Description
phospholipase A2, group XIIB
Omim ID
611653Gene Ontology
HyperlinkGene Summary
Phospholipase A2 (PLA2) enzymes catalyze hydrolysis of glycolipids to release free fatty acids and lysophospholipids. PLA2G12B belongs to the PLA2 family, but it is catalytically inactive due to an amino acid change in its active site and has altered phospholipid-binding properties (Rouault et al., 2003 [PubMed 14516201]).[supplied by OMIM
Other Designations
OTTHUMP00000019792|group XIII secreted phospholipase A2|phospholipase A2, group XIII
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Pathway
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Disease
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