DCLRE1C DNAxPab
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human DCLRE1C DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MSSFEGQMAEYPTISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLECSLKVYLYCSPVTKELLLTSPKYRFWKKRIISIEIETPTQISLVDEASGEKEEIVVTLLPAGHCPGSVMFLFQGNNGTVLYTGDFRLAQGEAARMELLHSGGRVKDIQSVYLDTTFCDPRFYQIPSREECLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFTNLSEELGVQVHVNKLDMFRNMPEILRHLTTDRNTQIHACRHPKAEEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGERSRKTNVIVRTGESSYRACFSFHSSYSEIKDFLSYLCPVNAYPNVIPVGTTMDKVVEILKPLCRSSQSTEPKYKPLGKLKRARTVHRDSGSHSVTQARMRWCHHDSLYPLTPGIKRSSCLSLLTSWITGAYRHAQLMI
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — DCLRE1C
Entrez GeneID
64421GeneBank Accession#
BC022254.1Protein Accession#
AAH22254.1Gene Name
DCLRE1C
Gene Alias
A-SCID, DCLREC1C, FLJ11360, FLJ36438, RS-SCID, SCIDA, SNM1C
Gene Description
DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae)
Gene Ontology
HyperlinkGene Summary
This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA). [provided by RefSeq
Other Designations
OTTHUMP00000019166|OTTHUMP00000019167|OTTHUMP00000019168|OTTHUMP00000019170|OTTHUMP00000019171|OTTHUMP00000019172|OTTHUMP00000019174|OTTHUMP00000045150|artemis protein|severe combined immunodeficiency, type a (Athabascan)
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Interactome
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Pathway
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Disease
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