GBA3 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of GBA3 expression in transfected 293T cell line (H00057733-T01) by GBA3 MaxPab polyclonal antibody.
Lane 1: GBA3 transfected lysate(17.82 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human GBA3 protein.
Immunogen
GBA3 (AAH29362.1, 1 a.a. ~ 162 a.a) full-length human protein.
Sequence
MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of GBA3 expression in transfected 293T cell line (H00057733-T01) by GBA3 MaxPab polyclonal antibody.
Lane 1: GBA3 transfected lysate(17.82 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — GBA3
Entrez GeneID
57733GeneBank Accession#
BC029362.1Protein Accession#
AAH29362.1Gene Name
GBA3
Gene Alias
CBGL1, GLUC, KLrP, MGC104276, MGC126878
Gene Description
glucosidase, beta, acid 3 (cytosolic)
Omim ID
606619Gene Ontology
HyperlinkGene Summary
GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 [PubMed 11389701]). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 [PubMed 17595169]).[supplied by OMIM
Other Designations
cytosolic beta-glucosidase|klotho-related protein
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Interactome
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Pathway
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