COQ3 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Western Blot (Cell lysate)
COQ3 MaxPab polyclonal antibody. Western Blot analysis of COQ3 expression in HeLa.
Western Blot (Transfected lysate)
Western Blot analysis of COQ3 expression in transfected 293T cell line (H00051805-T01) by COQ3 MaxPab polyclonal antibody.
Lane 1: COQ3 transfected lysate(40.59 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to COQ3 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human COQ3 protein.
Immunogen
COQ3 (AAH63463.1, 1 a.a. ~ 369 a.a) full-length human protein.
Sequence
MWSGRKLGSSGGWFLRVLGPGGCNTKAARPLISSAVYVKNQLSGTLQIKPGVFNEYRTIWFKSYRTIFSCLNRIKSFRYPWARLYSTSQTTVDSGEVKTFLALAHKWWDEQGVYAPLHSMNDLRVPFIRDNLLKTIPNHQPGKPLLGMKILDVGCGGGLLTEPLGRLGASVIGIDPVDENIKTAQCHKSFDPVLDKRIEYRVCSLEEIVEETAETFDAVVASEVVEHVIDLETFLQCCCQVLKPGGSLFITTINKTQLSYALGIVFSEQIAGIVPKGTHTWEKFVSPETLESILESNGLSVQTVVGMLYNPFSGYWHWSENTSLNYAAHAVKSRVQEHPASAEFVLKGETEELQANACTNPAVHEKLKK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (73); Rat (81)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
COQ3 MaxPab polyclonal antibody. Western Blot analysis of COQ3 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of COQ3 expression in transfected 293T cell line (H00051805-T01) by COQ3 MaxPab polyclonal antibody.
Lane 1: COQ3 transfected lysate(40.59 KDa).
Lane 2: Non-transfected lysate.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of purified MaxPab antibody to COQ3 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml] -
Gene Info — COQ3
Entrez GeneID
51805GeneBank Accession#
BC063463.1Protein Accession#
AAH63463.1Gene Name
COQ3
Gene Alias
UG0215E05, bA9819.1
Gene Description
coenzyme Q3 homolog, methyltransferase (S. cerevisiae)
Omim ID
605196Gene Ontology
HyperlinkGene Summary
Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM
Other Designations
OTTHUMP00000016892|methyltransferase COQ3
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Interactome
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