MRPL13 MaxPab mouse polyclonal antibody (B01)
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More Files
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Western Blot (Transfected lysate)
Western Blot analysis of MRPL13 expression in transfected 293T cell line (H00028998-T01) by MRPL13 MaxPab polyclonal antibody.
Lane 1: MRPL13 transfected lysate(19.58 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human MRPL13 protein.
Immunogen
MRPL13 (NP_054797.2, 1 a.a. ~ 178 a.a) full-length human protein.
Sequence
MSSFSRAPQQWATFARIWYLLDGKMQPPGKLAAMASIRLQGLHKPVYHALSDCGDHVVIMNTRHIAFSGNKWEQKVYSSHTGYPGGFRQVTAAQLHLRDPVAIVKLAIYGMLPKNLHRRTMMERLHLFPDEYIPEDILKNLVEELPQPRKIPKRLDEYTQEEIDAFPRLWTPPEDYRL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89); Rat (89)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of MRPL13 expression in transfected 293T cell line (H00028998-T01) by MRPL13 MaxPab polyclonal antibody.
Lane 1: MRPL13 transfected lysate(19.58 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — MRPL13
Entrez GeneID
28998GeneBank Accession#
NM_014078.4Protein Accession#
NP_054797.2Gene Name
MRPL13
Gene Alias
L13, L13A, L13mt, RPL13, RPML13
Gene Description
mitochondrial ribosomal protein L13
Omim ID
610200Gene Ontology
HyperlinkGene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Publication Reference
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NONO and RALY proteins are required for YB-1 oxaliplatin induced resistance in colon adenocarcinoma cell lines.
Tsofack SP, Garand C, Sereduk C, Chow D, Aziz M, Guay D, Yin HH, Lebel M.
Molecular Cancer 2011 Nov; 10:145.
Application：WB, Human, SW480, HT29 cells.
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NONO and RALY proteins are required for YB-1 oxaliplatin induced resistance in colon adenocarcinoma cell lines.
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