MORC1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human MORC1 partial ORF ( NP_055244, 1 a.a. - 100 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MDDRYPALQRAQLRLDFIHANSTTHSFLFGALAELLDNARDAGAERLDVFSVDNEKLQGGFMLCFLDDGCGMSPEEASDIIYFGRSKKRLSTLKFIGQYG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (66); Rat (67)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MORC1
Entrez GeneID
27136GeneBank Accession#
NM_014429Protein Accession#
NP_055244Gene Name
MORC1
Gene Alias
MORC, ZCW6
Gene Description
MORC family CW-type zinc finger 1
Omim ID
603205Gene Ontology
HyperlinkGene Summary
This gene encodes the human homolog of mouse morc and like the mouse protein it is testis-specific. Mouse studies support a testis-specific function since only male knockout mice are infertile; infertility is the only apparent defect. These studies further support a role for this protein early in spermatogenesis, possibly by affecting entry into apoptosis because testis from knockout mice show greatly increased numbers of apoptotic cells. [provided by RefSeq
Other Designations
microrchidia homolog|microrchidia, mouse, homolog of|microrchidia, mouse, honolog of
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Interactome
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Disease
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