KLK8 monoclonal antibody (M01), clone 2F11
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More Files
- More Functions
Western Blot (Cell lysate)
KLK8 monoclonal antibody (M01), clone 2F11 Western Blot analysis of KLK8 expression in A-431 ( Cat # L015V1 ).
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged KLK8 is approximately 0.3ng/ml as a capture antibody.
Immunofluorescence
Immunofluorescence of monoclonal antibody to KLK8 on A-431 cell. [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (37.62 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant KLK8.
Immunogen
KLK8 (NP_009127, 97 a.a. ~ 204 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
EIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (72); Rat (72)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.62 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
KLK8 monoclonal antibody (M01), clone 2F11 Western Blot analysis of KLK8 expression in A-431 ( Cat # L015V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged KLK8 is approximately 0.3ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to KLK8 on A-431 cell. [antibody concentration 10 ug/ml] -
Gene Info — KLK8
Entrez GeneID
11202GeneBank Accession#
NM_007196Protein Accession#
NP_009127Gene Name
KLK8
Gene Alias
HNP, NP, NRPN, PRSS19, TADG14
Gene Description
kallikrein-related peptidase 8
Omim ID
605644Gene Ontology
HyperlinkGene Summary
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in four transcript variants encoding four different isoforms. The isoforms exhibit distinct patterns of expression that suggest roles in brain plasticity and ovarian cancer. [provided by RefSeq
Other Designations
KLK8 protein type 1|KLK8 protein type 2|kallikrein 8|kallikrein 8 (neuropsin/ovasin)|neuropsin type 1|neuropsin type 2|ovasin|protease, serine, 19|tumor-associated differentially expressed gene 14
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Interactome
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Disease
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