TAF6L (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93); Rat (93)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of TAF6L transfected lysate using rabbit polyclonal anti-TAF6L and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-TAF6L.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-TAF6L (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-TAF6L (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — TAF6L
Entrez GeneID
10629Gene Name
TAF6L
Gene Alias
FLJ11136, MGC4288, PAF65A
Gene Description
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
Omim ID
602946Gene Ontology
HyperlinkGene Summary
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is a component of the PCAF histone acetylase complex and structurally similar to one of the histone-like TAFs, TAF6. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. [provided by RefSeq
Other Designations
TAF6-like RNA polymerase II|TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65 kD|p300/CBP-associated factor (PCAF)-associated factor 65
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Interactome
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Pathway
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