Products

Immunoprecipitation-Western Blot

Entrez GeneID

Gene Name

KLRG1

Gene Alias

2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE, MGC13600

Gene Description

killer cell lectin-like receptor subfamily G, member 1

Omim ID

Gene Ontology

Gene Summary

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. Alternatively spliced transcript variants have been reported, but their full-length natures have not yet been determined. [provided by RefSeq

Other Designations

C-type lectin domain family 15, member A|mast cell function-associated antigen (ITIM-containing)