Products

Western Blot (Transfected lysate)

Western Blot analysis of SLC25A27 expression in transfected 293T cell line (H00009481-T01) by SLC25A27 MaxPab polyclonal antibody.

Lane 1: SLC25A27 transfected lysate(27.06 KDa).
Lane 2: Non-transfected lysate.

Entrez GeneID

9481

GeneBank Accession#

BC033091

Protein Accession#

AAH33091

Gene Name

SLC25A27

Gene Alias

FLJ33552, UCP4

Gene Description

solute carrier family 25, member 27

Gene Ontology

Hyperlink

Gene Summary

Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. Transcripts of this gene are only detected in brain tissue and are specifically modulated by various environmental conditions. [provided by RefSeq

Other Designations

OTTHUMP00000016548|uncoupling protein 4