SLC9A3R1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
SDS-PAGE Gel
SLC9A3R1 transfected lysate.
Western Blot
Lane 1: SLC9A3R1 transfected lysate ( 38.9 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SLC9A3R1 full-length
Host
Human
Theoretical MW (kDa)
38.9
Interspecies Antigen Sequence
Mouse (86); Rat (87)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SLC9A3R1 antibody (H00009368-B01) by Western Blots.
SDS-PAGE Gel
SLC9A3R1 transfected lysate.
Western Blot
Lane 1: SLC9A3R1 transfected lysate ( 38.9 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SLC9A3R1
Entrez GeneID
9368GeneBank Accession#
NM_004252Protein Accession#
NP_004243Gene Name
SLC9A3R1
Gene Alias
EBP50, NHERF, NHERF1, NPHLOP2
Gene Description
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
Omim ID
604990Gene Ontology
HyperlinkGene Summary
This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer
Other Designations
sodium/hydrogen exchanger regulatory factor 1|solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1
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Interactome
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Disease
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