MAP3K13 monoclonal antibody (M04), clone 4H7
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MAP3K13.
Immunogen
MAP3K13 (NP_004712.1, 711 a.a. ~ 810 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SEPDKGQAGPWGCCQADAYDPCLQCRPEQYGSLDIPSAEPVGRSPDLSKSPAHNPLLENAQSSEKTEENEFSGCRSESSLGTSHLGTPPALPRKTRPLQK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89); Rat (87)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
MAP3K13 monoclonal antibody (M04), clone 4H7. Western Blot analysis of MAP3K13 expression in Jurkat.Western Blot (Transfected lysate)
Western Blot analysis of MAP3K13 expression in transfected 293T cell line by MAP3K13 monoclonal antibody (M04), clone 4H7.
Lane 1: MAP3K13 transfected lysate (Predicted MW: 108.3 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to MAP3K13 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — MAP3K13
Entrez GeneID
9175GeneBank Accession#
NM_004721Protein Accession#
NP_004712.1Gene Name
MAP3K13
Gene Alias
LZK, MGC133196
Gene Description
mitogen-activated protein kinase kinase kinase 13
Omim ID
604915Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway. [provided by RefSeq
Other Designations
leucine zipper-bearing kinase
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Interactome
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Pathway
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Disease
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