SLC7A7 monoclonal antibody (M04), clone 3B10
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SLC7A7.
Immunogen
SLC7A7 (NP_003973.2, 462 a.a. ~ 511 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RVPEHKRPLYLRRIVGSATRYLQVLCMSVAAEMDLEDGGEMPKQRDPKSN
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SLC7A7 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — SLC7A7
Entrez GeneID
9056GeneBank Accession#
NM_003982Protein Accession#
NP_003973.2Gene Name
SLC7A7
Gene Alias
LAT3, LPI, MOP-2, Y+LAT1, y+LAT-1
Gene Description
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000164491|OTTHUMP00000164492|OTTHUMP00000164494|monocyte amino acid permease 2|solute carrier family 7 member 7|y(+)L-type amino acid transporter 1
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Interactome
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Disease
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