DEGS1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human DEGS1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human DEGS1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human DEGS1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — DEGS1
Entrez GeneID
8560GeneBank Accession#
DEGS1Gene Name
DEGS1
Gene Alias
DEGS, DES1, Des-1, FADS7, MGC5079, MIG15, MLD
Gene Description
degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000035598|degenerative spermatocyte homolog 1, lipid desaturase|degenerative spermatocyte homolog, lipid desaturase|dihydroceramide desaturase|membrane fatty acid (lipid) desaturase|migration-inducing gene 15 protein|sphingolipid delta 4 desatura
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Interactome
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Pathway
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