Products

Western Blot (Transfected lysate)

Western Blot analysis of FGF23 expression in transfected 293T cell line (H00008074-T01) by FGF23 MaxPab polyclonal antibody.

Lane 1: FGF23 transfected lysate(27.61 KDa).
Lane 2: Non-transfected lysate.

In situ Proximity Ligation Assay (Cell)

Proximity Ligation Analysis of protein-protein interactions between FGFR2 and FGF23. HeLa cells were stained with anti-FGFR2 rabbit purified polyclonal 1:1200 and anti-FGF23 mouse purified polyclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).

Entrez GeneID

8074

GeneBank Accession#

NM_020638

Protein Accession#

NP_065689.1

Gene Name

FGF23

Gene Alias

ADHR, HPDR2, HYPF, PHPTC

Gene Description

fibroblast growth factor 23

Omim ID

193100 211900 605380

Gene Ontology

Hyperlink

Gene Summary

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The product of this gene inhibits renal tubular phosphate transport. This gene was identified by its mutations associated with autosomal dominant hypophosphatemic rickets (ADHR), an inherited phosphate wasting disorder. Abnormally high level expression of this gene was found in oncogenic hypophosphatemic osteomalacia (OHO), a phenotypically similar disease caused by abnormal phosphate metabolism. Mutations in this gene have also been shown to cause familial tumoral calcinosis with hyperphosphatemia. [provided by RefSeq

Other Designations

tumor-derived hypophosphatemia inducing factor