FGF23 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Western Blot
Lane 1: FGF23 transfected lysate ( 28 KDa)
Lane 2: Non-transfected lysate.
SDS-PAGE Gel
FGF23 transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-FGF23 full-length
Host
Human
Theoretical MW (kDa)
27.72
Interspecies Antigen Sequence
Mouse (71); Rat (72)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-FGF23 antibody (H00008074-B01) by Western Blots.
Western Blot
Lane 1: FGF23 transfected lysate ( 28 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
FGF23 transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — FGF23
Entrez GeneID
8074GeneBank Accession#
NM_020638Protein Accession#
NP_065689Gene Name
FGF23
Gene Alias
ADHR, HPDR2, HYPF, PHPTC
Gene Description
fibroblast growth factor 23
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The product of this gene inhibits renal tubular phosphate transport. This gene was identified by its mutations associated with autosomal dominant hypophosphatemic rickets (ADHR), an inherited phosphate wasting disorder. Abnormally high level expression of this gene was found in oncogenic hypophosphatemic osteomalacia (OHO), a phenotypically similar disease caused by abnormal phosphate metabolism. Mutations in this gene have also been shown to cause familial tumoral calcinosis with hyperphosphatemia. [provided by RefSeq
Other Designations
tumor-derived hypophosphatemia inducing factor
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Interactome
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Pathway
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Disease
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