TSC2 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (39.2 KDa) .
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Specifications
Product Description
Mouse polyclonal antibody raised against a partial recombinant TSC2.
Immunogen
TSC2 (NP_000539, 540 a.a. ~ 658 a.a) partial recombinant protein with GST tag.
Sequence
SPPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLFLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Rat (88)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (39.2 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — TSC2
Entrez GeneID
7249GeneBank Accession#
NM_000548Protein Accession#
NP_000539Gene Name
TSC2
Gene Alias
FLJ43106, LAM, TSC4
Gene Description
tuberous sclerosis 2
Gene Ontology
HyperlinkGene Summary
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
tuberin
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Interactomes
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Pathways
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Diseases
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