TSC2 recombinant monoclonal antibody, clone R04-1I3
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More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: Hela whole cell lysate, Lane 2: A549 whole cell lysate, Lane 3: HL-60 whole cell lysate and Lane 4: U2OS whole cell lysate with TSC2 recombinant monoclonal antibody, clone R04-1I3 (Cat # RAB04423).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human TSC2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human TSC2.
Theoretical MW (kDa)
Calculated MW: 201 k
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunoprecipitation (1:20)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane 1: Hela whole cell lysate, Lane 2: A549 whole cell lysate, Lane 3: HL-60 whole cell lysate and Lane 4: U2OS whole cell lysate with TSC2 recombinant monoclonal antibody, clone R04-1I3 (Cat # RAB04423).Immunoprecipitation
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Gene Info — TSC2
Entrez GeneID
7249Protein Accession#
P49815Gene Name
TSC2
Gene Alias
FLJ43106, LAM, TSC4
Gene Description
tuberous sclerosis 2
Gene Ontology
HyperlinkGene Summary
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
tuberin
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Interactome
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Pathway
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Disease
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