ROBO1 polyclonal antibody (A01)
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Specifications
Product Description
Mouse polyclonal antibody raised against a partial recombinant ROBO1.
Immunogen
ROBO1 (NP_002932, 491 a.a. ~ 589 a.a) partial recombinant protein with GST tag.
Sequence
DGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (96)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — ROBO1
Entrez GeneID
6091GeneBank Accession#
NM_002941Protein Accession#
NP_002932Gene Name
ROBO1
Gene Alias
DUTT1, FLJ21882, MGC131599, MGC133277, SAX3
Gene Description
roundabout, axon guidance receptor, homolog 1 (Drosophila)
Omim ID
602430Gene Ontology
HyperlinkGene Summary
Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
axon guidance receptor|roundabout 1
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Interactomes
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Pathways
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