RLN1 monoclonal antibody (M01), clone 1H6
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More Files
- More Functions
Immunoprecipitation
Immunoprecipitation of RLN1 transfected lysate using anti-RLN1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with RLN1 MaxPab rabbit polyclonal antibody.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged RLN1 is approximately 10ng/ml as a capture antibody.
Western Blot detection against Immunogen (43.12 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant RLN1.
Immunogen
RLN1 (AAH05956.1, 27 a.a. ~ 185 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
WKDDVIKLCGRELVRAQIAICGMSTWSKRSLSQEDAPQTPRPVAEIVPSFINKDTETIIIMLEFIANLPPELKAALSERQPSLPELQQYVPALKDSNLSFEEFKKLIRNRQSEAADSNPSELKYLGLDTHSQKKRRPYVALFEKCCLIGCTKRSLAKYC
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (43.12 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunoprecipitation
Immunoprecipitation of RLN1 transfected lysate using anti-RLN1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with RLN1 MaxPab rabbit polyclonal antibody.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged RLN1 is approximately 10ng/ml as a capture antibody.ELISA
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Gene Info — RLN1
Entrez GeneID
6013GeneBank Accession#
BC005956Protein Accession#
AAH05956.1Gene Name
RLN1
Gene Alias
H1, RLXH1, bA12D24.3.1, bA12D24.3.2
Gene Description
relaxin 1
Omim ID
179730Gene Ontology
HyperlinkGene Summary
Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. This encoded protein is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds; however, their exact cleavage sites have not been described. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. This gene has multiple polyadenylation sites. There are multiple alternatively spliced transcript variants described for this gene but their full length nature is not known yet. [provided by RefSeq
Other Designations
OTTHUMP00000021026|preprorelaxin H1|prorelaxin|relaxin H1
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Interactome
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Disease
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