RECQL monoclonal antibody (M07), clone 4D5
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant RECQL.
Immunogen
RECQL (NP_116559.1, 549 a.a. ~ 648 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
FLIQQYLKEDYSFTAYATISYLKIGPKANLLNNEAHAITMQVTKSTQNSFRAESSQTCHSEQGDKKMEEKNSGNFQKKAANMLQQSGSKNTGAKKRKIDD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (68); Rat (65)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged RECQL is 3 ng/ml as a capture antibody.ELISA
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Gene Info — RECQL
Entrez GeneID
5965GeneBank Accession#
NM_032941Protein Accession#
NP_116559.1Gene Name
RECQL
Gene Alias
RECQL1, RecQ1
Gene Description
RecQ protein-like (DNA helicase Q1-like)
Omim ID
600537Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' and 3' UTRs, have been described. [provided by RefSeq
Other Designations
ATP-dependent DNA helicase Q1|DNA helicase Q1-like|RecQ protein-like
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Interactome
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Disease
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